There is growing consensus that genome organization and long-range gene regulation involves partitioning of the genome into domains of distinct epigenetic chromatin states.Chromatin insulator or barrier elements are key components of these processes as they can establish boundaries between chromatin states.The ability of elements such as the paradi
Management of High Blood Pressure in Those without Overt Cardiovascular Disease Utilising Absolute Risk Scores
Increasing blood pressure has a continuum of adverse risk for cardiovascular events.Traditionally this single measure was used to determine who to treat Baking and how vigorously.However, estimating absolute risk rather than measurement of a single risk factor such as blood pressure is a superior method to identify who is most at risk of having an
Adaptation of consumer law to the digital age: EU Directive 2019/2161 on modernisation and better enforcement of consumer law
This Paper examines the most important innovations in the recently adopted European Directive 2019/2161 on better enforcement and modernisation of Union consumer protection rules.First, Hygiene by adding the innovative rules, such as the ones on the trustworthiness of online reviews, the Directive aims to adapt the European regulatory framework on
Global migration and factors that support acculturation and retention of international nurses: A systematic review
Background: International nurses (migrant nurses who are recruited to work in different countries) make essential contributions to global health and care workforces that are experiencing domestic nurse shortages.Global recruitment and migration is increasing, and with growing dependency on international nurses, health and care employers must unders
Single-end hybrid Rayleigh Brillouin and Raman distributed fibre-optic sensing system
Backscattered lightwaves from an optical fibre are used to realise distributed fibre optic sensing (DFOS) systems for measuring various parameters.Rayleigh, Brillouin, and Raman backscattering provide different sensitivities to different measurands and have garnered the attention of researchers.A system combining the three principles above can effe